'Shine through' on dual tracer parathyroid scintigraphy: A potential pitfall in interpretation

Yiyan Liu; K. J. Chun; Leonard M. Freeman

doi:10.1097/00003072-200503000-00001

'Shine through' on dual tracer parathyroid scintigraphy: A potential pitfall in interpretation

Yiyan Liu, K. J. Chun, Leonard M. Freeman

Radiology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Dual tracer scintigraphy has become the procedure of choice for preoperative localization of parathyroid adenomas. The typical protocol used by most laboratories is to initially perform a Tc-99m sestamibi (MIBI) study with early and delayed (2-3 hours) washout phase images. This is followed by a thyroid-specific Tc-99m pertechnetate study. A potential pitfall exists if the delayed phase of the initial MIBI study shows an intense, abnormal focus of retention. This focus may interfere with interpretation of the subsequent pertechnetate study because of a "shine through" effect. To differentiate a parathyroid adenoma from a thyroid adenoma, it may be necessary to repeat the thyroid-specific pertechnetate scan on a separate day after the dual tracer study.

Original language	English (US)
Pages (from-to)	145-149
Number of pages	5
Journal	Clinical nuclear medicine
Volume	30
Issue number	3
DOIs	https://doi.org/10.1097/00003072-200503000-00001
State	Published - Mar 2005

Keywords

Parathyroid adenoma
Parathyroid scan
Thyroid adenoma

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/00003072-200503000-00001

Cite this

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abstract = "Dual tracer scintigraphy has become the procedure of choice for preoperative localization of parathyroid adenomas. The typical protocol used by most laboratories is to initially perform a Tc-99m sestamibi (MIBI) study with early and delayed (2-3 hours) washout phase images. This is followed by a thyroid-specific Tc-99m pertechnetate study. A potential pitfall exists if the delayed phase of the initial MIBI study shows an intense, abnormal focus of retention. This focus may interfere with interpretation of the subsequent pertechnetate study because of a {"}shine through{"} effect. To differentiate a parathyroid adenoma from a thyroid adenoma, it may be necessary to repeat the thyroid-specific pertechnetate scan on a separate day after the dual tracer study.",

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AU - Chun, K. J.

AU - Freeman, Leonard M.

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AB - Dual tracer scintigraphy has become the procedure of choice for preoperative localization of parathyroid adenomas. The typical protocol used by most laboratories is to initially perform a Tc-99m sestamibi (MIBI) study with early and delayed (2-3 hours) washout phase images. This is followed by a thyroid-specific Tc-99m pertechnetate study. A potential pitfall exists if the delayed phase of the initial MIBI study shows an intense, abnormal focus of retention. This focus may interfere with interpretation of the subsequent pertechnetate study because of a "shine through" effect. To differentiate a parathyroid adenoma from a thyroid adenoma, it may be necessary to repeat the thyroid-specific pertechnetate scan on a separate day after the dual tracer study.

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'Shine through' on dual tracer parathyroid scintigraphy: A potential pitfall in interpretation

Abstract

Keywords

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