Serotonergic medications for sexual obsessions, sexual addictions, and paraphilias

D. J. Stein, E. Hollander, D. T. Anthony, F. R. Schneier, B. A. Fallon, M. R. Liebowitz, D. F. Klein

Research output: Contribution to journalArticlepeer-review

166 Scopus citations


Background: Paraphilias and related disorders have recently been thought of as sexual addictions. However, it has also been argued that these disorders are sexual compulsions. The question arises as to whether these disorders and obsessive compulsive disorder respond in the same way to pharmacotherapy. Method: We retrospectively reviewed outcome in 13 patients who presented with sexual symptoms and were treated with serotonin reuptake blockers. Symptoms were divided into paraphilias, nonparaphilic sexual addictions, and sexual obsessions. Results: Paraphilias had the least improvement, while sexual obsessions had the best response to medication. Conclusion: Paraphilias and related disorders may be less responsive than sexual obsessions or compulsions to serotonin reuptake blockers. Perhaps paraphilias and related disorders are on the impulsive rather than the compulsive end of the spectrum of obsessive compulsive disorders. Controlled trials are, however, necessary to replicate these preliminary findings.

Original languageEnglish (US)
Pages (from-to)267-271
Number of pages5
JournalJournal of Clinical Psychiatry
Issue number8
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


Dive into the research topics of 'Serotonergic medications for sexual obsessions, sexual addictions, and paraphilias'. Together they form a unique fingerprint.

Cite this