Selective counterregulatory hormone responses after oral glucose in man

Jerry Kleinbaum, Harry Shamoon

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


The plasma response of various counterregulatory hormones was measured after an oral glucose tolerance test in 19 normal subjects. Significant elevations in plasma epinephrine (P < 0.05) and human GH (P < 0.05) were observed late in the course of the oral glucose tolerance test coincident with the fall in plasma glucose. Plasma norepinephrine, glucagon, and cortisol levels did not change during the latter phase of the test. The elevations in plasma human GH and epinephrine levels were unrelated to either absolute hypoglycemia or to clinical symptoms of hypoglycemia. These data suggest a possible role for adrenergic mechanisms in glucose counterregulation under physiological conditions.

Original languageEnglish (US)
Pages (from-to)787-790
Number of pages4
JournalJournal of Clinical Endocrinology and Metabolism
Issue number4
StatePublished - Oct 1982
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical


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