Seizing control of epileptic activity can improve outcome

Kevin E. Chapman, Nicola Specchio, Shlomo Shinnar, Gregory L. Holmes

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


In epileptic encephalopathy, the seizures and interictal epileptiform activity create additional neurocognitive dysfunction beyond that due to the underlying etiology. Treatment leading to a reduction in seizures or interictal abnormalities may help improve neurocognitive function in these situations. The focus of our discussion is reviewing data that support the concept that treatment can impact outcome independent of the etiology in some cases.

Original languageEnglish (US)
Pages (from-to)1482-1485
Number of pages4
Issue number10
StatePublished - Oct 1 2015


  • Cognitive impairment
  • Epilepsy
  • Epileptic encephalopathy
  • Humans
  • Treatment

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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