Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome

P. Singer, M. M. Rothkopf, V. Kvetan, O. Kirvela, J. Gaare, J. Askanazi

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


The gastrointestinal tract is a major target of the human immunodeficiency virus. Many AIDS patients have weight loss and/or diarrhea. Parenteral nutrition can be used to treat malnutrition associated with malabsorption. We reviewed retrospectively the clinical course of 22 patients with AIDS and weight loss greater than 10% who received home parenteral nutrition (HPN) for 56.2 patient-months. Mean weight loss was 21.4%, mean duration of HPN 2.55 months, mean age 37.4 years. Fifteen patients gained weight, six stabilized and two continued to lose weight. Nine patients returned to previous activity. Five died. The rates of catheter-related sepsis, complications, and metabolic disturbances were 0.12, 0.25, and 0.12/100 catheter days, respectively, results identical to those reported in other patient populations where HPN is commonly applied. We found that HPN induced weight gain and clinical improvement in most patients without higher risks of sepsis than in patients with malignancies.

Original languageEnglish (US)
Pages (from-to)75-79
Number of pages5
JournalJournal of Parenteral and Enteral Nutrition
Issue number1
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


Dive into the research topics of 'Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome'. Together they form a unique fingerprint.

Cite this