Reversible Symptomatic Biliary Obstruction Associated with Ceftriaxone Pseudolithiasis

Jonathan Zinberg, Richard Chernaik, Eugene Coman, Ruth Rosenblatt, Lawrence J. Brandt

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


Ceftriaxone, a third‐generation cephalosporin, has been associated with the development of sludge or stones in the gallbladders of some patients treated with this medication. Such precipitates, which are usually reversible upon discontinuation of the drug, sometimes cause symptoms, have simulated acute cholecystitis, and have even led to cholecystectomy in some cases. We report the first known instance of biliary obstruction and secondary pancreatitis in association with reversible ceftriaxone‐induced pseudolithiasis.

Original languageEnglish (US)
Pages (from-to)1251-1254
Number of pages4
JournalThe American Journal of Gastroenterology
Issue number9
StatePublished - Sep 1991

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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