Reversible opacification of a hydrophilic acrylic intraocular lens

Choul Yong Park, Roy S. Chuck

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A 56-year-old woman with diabetic retinopathy and chronic myelogenous leukemia had phacoemulsification cataract removal and hydrophilic acrylic intraocular lens (IOL) (Akreos MI-60) implantation in both eyes. One month after surgery, significant IOL opacity and severe cystoid macular edema were observed in both eyes. After bilateral intravitreal injection of bevacizumab (Avastin) to control macular edema, central clearing of the IOL opacity was observed in both eyes. Two months after the injection, the IOL opacity had almost disappeared from both eyes. To our knowledge, this is the first case of early postoperative bilateral IOL opacity in a hydrophilic acrylic IOL cleared after anti-vascular endothelial growth factor (VEGF) intravitreal injection. The role of anti-VEGF therapy in clearing IOL opacification requires further investigation. Financial Disclosure: Neither author has a financial or proprietary interest in any material or method mentioned.

Original languageEnglish (US)
Pages (from-to)166-169
Number of pages4
JournalJournal of cataract and refractive surgery
Issue number1
StatePublished - Jan 2012

ASJC Scopus subject areas

  • Medicine(all)


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