Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients

Gunjan Garg; Raphaella DaSilva; Mimi Kim; Charito Love; Tony Abraham

doi:10.1016/j.clinimag.2016.12.003

Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients

Gunjan Garg, Raphaella DaSilva, Mimi Kim, Charito Love, Tony Abraham

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Objective To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications. Methods 57 patients with focally increased FDG activity in bones and a definite follow up were included. Results 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%. Conclusion Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.

Original language	English (US)
Pages (from-to)	138-146
Number of pages	9
Journal	Clinical Imaging
Volume	42
DOIs	https://doi.org/10.1016/j.clinimag.2016.12.003
State	Published - Mar 1 2017

Keywords

Bone metastases
CT correlate
FDG PET

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2016.12.003

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title = "Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients",

abstract = "Objective To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications. Methods 57 patients with focally increased FDG activity in bones and a definite follow up were included. Results 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%. Conclusion Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.",

keywords = "Bone metastases, CT correlate, FDG PET",

author = "Gunjan Garg and Raphaella DaSilva and Mimi Kim and Charito Love and Tony Abraham",

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year = "2017",

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doi = "10.1016/j.clinimag.2016.12.003",

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T1 - Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients

AU - Garg, Gunjan

AU - DaSilva, Raphaella

AU - Kim, Mimi

AU - Love, Charito

AU - Abraham, Tony

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Objective To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications. Methods 57 patients with focally increased FDG activity in bones and a definite follow up were included. Results 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%. Conclusion Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.

AB - Objective To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications. Methods 57 patients with focally increased FDG activity in bones and a definite follow up were included. Results 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%. Conclusion Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.

KW - Bone metastases

KW - CT correlate

KW - FDG PET

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JO - Clinical Imaging

JF - Clinical Imaging

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Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients

Abstract

Keywords

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