Reduced-representation methylation mapping

Jeffrey A. Jeddeloh; John M. Greally; Oliver J. Rando

doi:10.1186/gb-2008-9-8-231

Reduced-representation methylation mapping

Jeffrey A. Jeddeloh, John M. Greally, Oliver J. Rando

Genetics

Research output: Contribution to journal › Short survey › peer-review

23 Scopus citations

Abstract

The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.

Original language	English (US)
Article number	231
Journal	Genome biology
Volume	9
Issue number	8
DOIs	https://doi.org/10.1186/gb-2008-9-8-231
State	Published - Sep 1 2008

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/gb-2008-9-8-231

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title = "Reduced-representation methylation mapping",

abstract = "The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.",

author = "Jeddeloh, {Jeffrey A.} and Greally, {John M.} and Rando, {Oliver J.}",

note = "Funding Information: JMG is supported by grants from the National Institutes of Health (NIH, R01 HD044078, R01 HG004401, R21 CA122339), and the High-Q Foundation. OJR is supported by a Career Award in the Biomedical Sciences from the Burroughs Wellcome Fund, and by grants from the NIH (R01 GM079205 and NIH Roadmap grant U54 RR020839).",

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AU - Jeddeloh, Jeffrey A.

AU - Greally, John M.

AU - Rando, Oliver J.

N1 - Funding Information: JMG is supported by grants from the National Institutes of Health (NIH, R01 HD044078, R01 HG004401, R21 CA122339), and the High-Q Foundation. OJR is supported by a Career Award in the Biomedical Sciences from the Burroughs Wellcome Fund, and by grants from the NIH (R01 GM079205 and NIH Roadmap grant U54 RR020839).

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N2 - The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.

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Reduced-representation methylation mapping

Abstract

ASJC Scopus subject areas

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