Receptor-effector coupling by G-proteins implications for endocrinology

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Discovered serendipitously in the course of studies on the mechanism of glucagon stimulation of hepatic cyclic AMP formation, G-proteins have emerged as an expanding family of signal transducers, coupling diverse receptors and effectors. Quantitative and/or qualitative changes in G-proteins may profoundly affect hormone action, and can lead to clinically apparent endocrine dysfunction.

Original languageEnglish (US)
Pages (from-to)72-76
Number of pages5
JournalTrends in Endocrinology and Metabolism
Issue number2
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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