TY - JOUR
T1 - Rapid degeneration of ampullary electroreceptor organs after denervation
AU - Bruce Szamier, R.
AU - Bennett, Michael V.L.
PY - 1973/2/1
Y1 - 1973/2/1
N2 - Electroreceptors (ampullary organs) of the transparent catfish (Kryptopterus bidrrhus) lie in the epidermis, and contain spherical receptor cells that receive purely afferent innervation from the lateral line nerve. Section of this nerve causes rapid degenerative changes to occur in the receptors. Fine structural alterations occur in the receptor cell synapses and nerve fiber 6-12 h postoperatively. Disruption of the receptor cells begins by 18 h and most are lost by 48 h. By 72 h supporting cells and secretory cells also show marked degeneration, and by 96 h they may be totally lost. The rapid degeneration of the electroreceptor organs of Kryptopterus should make them a useful preparation for analysis of neurotrophic functions.
AB - Electroreceptors (ampullary organs) of the transparent catfish (Kryptopterus bidrrhus) lie in the epidermis, and contain spherical receptor cells that receive purely afferent innervation from the lateral line nerve. Section of this nerve causes rapid degenerative changes to occur in the receptors. Fine structural alterations occur in the receptor cell synapses and nerve fiber 6-12 h postoperatively. Disruption of the receptor cells begins by 18 h and most are lost by 48 h. By 72 h supporting cells and secretory cells also show marked degeneration, and by 96 h they may be totally lost. The rapid degeneration of the electroreceptor organs of Kryptopterus should make them a useful preparation for analysis of neurotrophic functions.
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U2 - 10.1083/jcb.56.2.466
DO - 10.1083/jcb.56.2.466
M3 - Article
C2 - 4345554
AN - SCOPUS:0015576304
SN - 0021-9525
VL - 56
SP - 466
EP - 477
JO - Journal of Cell Biology
JF - Journal of Cell Biology
IS - 2
ER -