Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer

Medicine & Life Sciences

• Quassins 100%
• bruceantinol 74%
• Protein Biosynthesis 59%
• Colorectal Neoplasms 43%
• Homoharringtonine 25%
• Protein Synthesis Inhibitors 19%
• Proteins 17%
• napabucasin 16%
• Cell Proliferation 15%
• Nanoparticles 6%
• Small Interfering RNA 6%
• Colon 6%
• Spleen 6%
• Epithelial Cells 5%
• Body Weight 5%
• Therapeutics 5%
• Neoplasms 4%
• Weights and Measures 4%
• Cell Line 4%
• Growth 3%

Chemical Compounds

• Quassinoid 86%
• Bruceantinol 59%
• Protein Synthesis 56%
• Antitumor 50%
• Protein Synthesis Inhibitor 29%
• STAT3 Inhibitor 17%
• Silencing RNA 11%
• Encapsulation 7%
• Weight 4%
• Nanoparticle 4%