Pulmonary Mycobacterium kyorinense disease: A case report and review of literature

Rajagopalan Saranathan, Chandrasekaran Padmapriyadarsini, Gomathi Sivaramakrishnan, Bhavani Perumal, Silambuchelvi Kannayan, Bency Joseph, Narendran Gopalan, Luke Hanna

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We report here the first case of pulmonary infection due to Mycobacterium kyorinense in a 55-year-old hypertensive woman treated for pulmonary tuberculosis earlier on two occasions. She presented with productive cough, intermittent episode of left-sided chest pain, loss of appetite, low-grade fever, and breathlessness. Sputum cultures revealed non-tuberculous mycobacteria (NTM). She remained persistently symptomatic with sputum cultures positive for acid-fast bacilli even after 6 months of treatment. Hence, a 16SrRNA gene amplification and sequencing were done that revealed M. kyorinense. Based on the guidelines of the American Thoracic Society, she was started on weight-based dosing of clarithromycin, levofloxacin, ethambutol, isoniazid and injection amikacin daily. The patient improved symptomatically and became culture-negative after 3 months of therapy with the above regimen and continued to be culture negative for 12 months of treatment. She continues to remain symptom-free without evidence of any clinical or bacteriological relapse.

Original languageEnglish (US)
Pages (from-to)127-131
Number of pages5
JournalIndian Journal of Medical Microbiology
Issue number1
StatePublished - Jan 1 2019
Externally publishedYes


  • 16SrRNA
  • non-tuberculous mycobacteria
  • rifampicin resistance

ASJC Scopus subject areas

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • Immunology and Microbiology (miscellaneous)
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases


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