Abstract
We report here the first case of pulmonary infection due to Mycobacterium kyorinense in a 55-year-old hypertensive woman treated for pulmonary tuberculosis earlier on two occasions. She presented with productive cough, intermittent episode of left-sided chest pain, loss of appetite, low-grade fever, and breathlessness. Sputum cultures revealed non-tuberculous mycobacteria (NTM). She remained persistently symptomatic with sputum cultures positive for acid-fast bacilli even after 6 months of treatment. Hence, a 16SrRNA gene amplification and sequencing were done that revealed M. kyorinense. Based on the guidelines of the American Thoracic Society, she was started on weight-based dosing of clarithromycin, levofloxacin, ethambutol, isoniazid and injection amikacin daily. The patient improved symptomatically and became culture-negative after 3 months of therapy with the above regimen and continued to be culture negative for 12 months of treatment. She continues to remain symptom-free without evidence of any clinical or bacteriological relapse.
Original language | English (US) |
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Pages (from-to) | 127-131 |
Number of pages | 5 |
Journal | Indian Journal of Medical Microbiology |
Volume | 37 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2019 |
Externally published | Yes |
Keywords
- 16SrRNA
- non-tuberculous mycobacteria
- rifampicin resistance
ASJC Scopus subject areas
- Immunology and Allergy
- Microbiology
- Immunology
- Immunology and Microbiology (miscellaneous)
- General Immunology and Microbiology
- Microbiology (medical)
- Infectious Diseases