TY - JOUR
T1 - Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort
AU - the SPARK Consortium
AU - Fombonne, Eric
AU - Green Snyder, Lee Anne
AU - Daniels, Amy
AU - Feliciano, Pamela
AU - Chung, Wendy
AU - Abbeduto, Leonard
AU - Aberbach, Gabriella
AU - Acampado, John
AU - Ace, Andrea J.
AU - Albright, Charles
AU - Alessandri, Michael
AU - Amaral, David G.
AU - Amatya, Alpha
AU - Anglo, Claudine
AU - Annett, Robert D.
AU - Arriaga, Ivette
AU - Ashley, Raven
AU - Astrovskaya, Irina
AU - Baalman, Kelly
AU - Baer, Melissa
AU - Bahl, Ethan
AU - Balasubramanian, Adithya
AU - Baraghoshi, Gabrielle
AU - Bardett, Nicole
AU - Barnard, Rebecca A.
AU - Bashar, Asif
AU - Beaudet, Arthur
AU - Beckwith, Malia
AU - Beeson, Landon
AU - Bentley, Dawn
AU - Bernier, Raphael A.
AU - Berry-Kravis, Elizabeth
AU - Boland, Sarah
AU - Booker, Stephanie
AU - Bradley, Catherine
AU - Brewster, Stephanie J.
AU - Brooks, Elizabeth
AU - Brown, Melissa
AU - Brueggeman, Leo
AU - Butler, Martin E.
AU - Butter, Eric M.
AU - Callahan, Kristen
AU - Camba, Alexies
AU - Carbone, Paul
AU - Carpenter, Laura
AU - Carpenter, Sarah
AU - Carriero, Nicholas
AU - Cartner, Lindsey A.
AU - Shulman, Lisa
AU - Valicenti-McDermott, Maria
N1 - Publisher Copyright:
© 2020, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2917 autistic adults participating in the US research cohort SPARK. Participants were 78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity.
AB - This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2917 autistic adults participating in the US research cohort SPARK. Participants were 78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity.
KW - Adult
KW - Autism
KW - Autism spectrum disorder
KW - Intellectual disabilities
KW - Medical
KW - Psychiatric
KW - SPARK
KW - Sex
UR - http://www.scopus.com/inward/record.url?scp=85081004851&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85081004851&partnerID=8YFLogxK
U2 - 10.1007/s10803-020-04414-6
DO - 10.1007/s10803-020-04414-6
M3 - Article
C2 - 32096123
AN - SCOPUS:85081004851
SN - 0162-3257
VL - 50
SP - 3679
EP - 3698
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 10
ER -