Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.

J. H. Oppenheimer; H. L. Schwartz; M. I. Surks

doi:10.1172/JCI107063

Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.

J. H. Oppenheimer, H. L. Schwartz, M. I. Surks

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	2493-2497
Number of pages	5
Journal	The Journal of clinical investigation
Volume	51
Issue number	9
DOIs	https://doi.org/10.1172/JCI107063
State	Published - 1972
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1172/JCI107063

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Oppenheimer, J. H., Schwartz, H. L., & Surks, M. I. (1972). Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone. The Journal of clinical investigation, 51(9), 2493-2497. https://doi.org/10.1172/JCI107063

Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone. / Oppenheimer, J. H.; Schwartz, H. L.; Surks, M. I.
In: The Journal of clinical investigation, Vol. 51, No. 9, 1972, p. 2493-2497.

Research output: Contribution to journal › Article › peer-review

Oppenheimer, JH, Schwartz, HL & Surks, MI 1972, 'Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.', The Journal of clinical investigation, vol. 51, no. 9, pp. 2493-2497. https://doi.org/10.1172/JCI107063

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Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.

ASJC Scopus subject areas

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