Primary ablation for ventricular tachycardia: When and how?

Pasquale Santangeli, Luigi Di Biase, Amin Al-Ahmad, Henry Hsia, J. David Burkhardt, Javier Sanchez, Rong Bai, Michela Casella, Antonio Dello Russo, Claudio Tondo, Andrea Natale

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Catheter ablation of ventricular tachycardia (VT) has improved arrhythmia-free survival in patients with multiple VT episodes refractory to antiarrhythmic drugs. Recent studies have evaluated the role of early intervention with catheter ablation in patients experiencing a single episode of life-threatening ventricular arrhythmias and undergoing secondary prevention defibrillator implantation. Such "primary VT ablation" strategy has proven effective in reducing the VT recurrence rate compared with standard medical therapy (no antiarrhythmic drug). This article summarizes the evidence on primary VT ablation and discusses its clinical indications and outcomes compared with standard catheter ablation of drug-refractory recurrent VT (ie, secondary VT ablation).

Original languageEnglish (US)
Pages (from-to)675-688
Number of pages14
JournalCardiac Electrophysiology Clinics
Issue number4
StatePublished - Dec 2011
Externally publishedYes


  • Cardiac arrest
  • Catheter ablation
  • Ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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