Preproenkephalin mRNA in T‐Cells, macrophages, and mast cells

J. Martin, M. B. Prystowsky, R. H. Angeletti

Research output: Contribution to journalArticlepeer-review

57 Scopus citations


The presence of preproenkephaline mRNA in tumor cell lines derived from myeloid and mast cells was analyzed by RNA dot blot hybridization. A B‐cell lymphoma was negative for preproenkephalin mRNA, but several T‐cell lymphomas were positive. A mastocytoma and two macrophage cell lines were found to have high levels of preproenkephalin mRNA. Purified natural macrophages and mast cells also possessed easily detectable levels of this mRNA.

Original languageEnglish (US)
Pages (from-to)82-87
Number of pages6
JournalJournal of Neuroscience Research
Issue number1
StatePublished - 1987
Externally publishedYes


  • macrophages
  • mast cell
  • opiate peptides
  • preproenkephalin

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience


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