TY - JOUR
T1 - Predictors of major depression six months after admission for outpatient treatment
AU - Weinberger, Mark I.
AU - Sirey, Jo Anne
AU - Bruce, Martha L.
AU - Heo, Moonseong
AU - Papademetriou, Eros
AU - Meyers, Barnett S.
PY - 2008/10
Y1 - 2008/10
N2 - Objective: This study examined the rate and predictors of major depression six months after outpatient mental health admission. Methods: Assessments were conducted at admission and three and six months later among 166 participants. Antidepressant treatment adequacy and depression outcomes were assessed at followups. Results: Predictors of major depression at six months included nonremission status at three months (odds ratio [OR]=3.56, p=.003), inadequacy of early pharmacotherapy (OR=2.73, p=.009), worse physical functioning measured by the 36-Item Short-Form Health Survey (OR=.975, p<.001), and being unmarried (OR=2.54, p=.031). Conclusions: The findings support the effects of baseline physical disability, marital status, early treatment adequacy, and early remission on the course of major depression. The identification of individuals who do not receive intensive pharmacotherapy or who have not recovered by three months may provide opportunities for interventions to optimize six-month outcomes and to prevent the development of a persistent depression.
AB - Objective: This study examined the rate and predictors of major depression six months after outpatient mental health admission. Methods: Assessments were conducted at admission and three and six months later among 166 participants. Antidepressant treatment adequacy and depression outcomes were assessed at followups. Results: Predictors of major depression at six months included nonremission status at three months (odds ratio [OR]=3.56, p=.003), inadequacy of early pharmacotherapy (OR=2.73, p=.009), worse physical functioning measured by the 36-Item Short-Form Health Survey (OR=.975, p<.001), and being unmarried (OR=2.54, p=.031). Conclusions: The findings support the effects of baseline physical disability, marital status, early treatment adequacy, and early remission on the course of major depression. The identification of individuals who do not receive intensive pharmacotherapy or who have not recovered by three months may provide opportunities for interventions to optimize six-month outcomes and to prevent the development of a persistent depression.
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U2 - 10.1176/ps.2008.59.10.1211
DO - 10.1176/ps.2008.59.10.1211
M3 - Article
C2 - 18832510
AN - SCOPUS:53549115367
SN - 1075-2730
VL - 59
SP - 1211
EP - 1215
JO - Psychiatric Services
JF - Psychiatric Services
IS - 10
ER -