Post-dural puncture headache: Part II - Prevention, management, and prognosis

David Bezov, Sait Ashina, Richard Lipton

Research output: Contribution to journalReview articlepeer-review

117 Scopus citations


Post-dural puncture headache (PDPH) is a frequent complication of lumbar puncture, performed for diagnostic or therapeutic purposes or accidentally, as a complication of epidural anesthesia. As PDPH can be disabling, clinicians who perform these procedures should be familiar with strategies for preventing this disorder. Since the best preventative measures sometimes fail, clinicians should also be familiar with the therapeutic approaches for PDPH. Herein, we review the procedure-related risk factors for PDPH, the prognosis of PDPH and the studies of PDPH treatment. We divide the therapeutic approach to PDPH into 4 stages: conservative management, aggressive medical management, conventional invasive treatments, and the very rarely employed less conventional invasive treatments and provide management algorithm to facilitate treatment.

Original languageEnglish (US)
Pages (from-to)1482-1498
Number of pages17
Issue number9
StatePublished - Oct 2010


  • post-dural puncture headache prevention
  • post-dural puncture prognosis
  • post-dural puncture treatment

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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