Polymorphic transformation of artemisinin by high temperature extrusion

Chaitrali Kulkarni; John Kendrick; Adrian Kelly; Tim Gough; Radha Charan Dash; Anant Paradkar

doi:10.1039/c3ce40726h

Polymorphic transformation of artemisinin by high temperature extrusion

Chaitrali Kulkarni, John Kendrick, Adrian Kelly, Tim Gough, Radha Charan Dash, Anant Paradkar

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

This communication reports a novel solvent free method to generate and stabilise the triclinic form of artemisinin. We show that the stability of the triclinic form obtained by high temperature extrusion is greater than that of material made using a solvent based technique.

Original language	English (US)
Pages (from-to)	6297-6300
Number of pages	4
Journal	CrystEngComm
Volume	15
Issue number	32
DOIs	https://doi.org/10.1039/c3ce40726h
State	Published - 2013
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Materials Science
Condensed Matter Physics

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10.1039/c3ce40726h

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title = "Polymorphic transformation of artemisinin by high temperature extrusion",

abstract = "This communication reports a novel solvent free method to generate and stabilise the triclinic form of artemisinin. We show that the stability of the triclinic form obtained by high temperature extrusion is greater than that of material made using a solvent based technique.",

author = "Chaitrali Kulkarni and John Kendrick and Adrian Kelly and Tim Gough and Dash, {Radha Charan} and Anant Paradkar",

year = "2013",

doi = "10.1039/c3ce40726h",

language = "English (US)",

volume = "15",

pages = "6297--6300",

journal = "CrystEngComm",

issn = "1466-8033",

publisher = "Royal Society of Chemistry",

number = "32",

}

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T1 - Polymorphic transformation of artemisinin by high temperature extrusion

AU - Kulkarni, Chaitrali

AU - Kendrick, John

AU - Kelly, Adrian

AU - Gough, Tim

AU - Dash, Radha Charan

AU - Paradkar, Anant

PY - 2013

Y1 - 2013

N2 - This communication reports a novel solvent free method to generate and stabilise the triclinic form of artemisinin. We show that the stability of the triclinic form obtained by high temperature extrusion is greater than that of material made using a solvent based technique.

AB - This communication reports a novel solvent free method to generate and stabilise the triclinic form of artemisinin. We show that the stability of the triclinic form obtained by high temperature extrusion is greater than that of material made using a solvent based technique.

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UR - http://www.scopus.com/inward/citedby.url?scp=84881457116&partnerID=8YFLogxK

U2 - 10.1039/c3ce40726h

DO - 10.1039/c3ce40726h

M3 - Article

AN - SCOPUS:84881457116

SN - 1466-8033

VL - 15

SP - 6297

EP - 6300

JO - CrystEngComm

JF - CrystEngComm

IS - 32

ER -

Polymorphic transformation of artemisinin by high temperature extrusion

Abstract

ASJC Scopus subject areas

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