Perihepatitis Associated With Salpingitis in Adolescents

Iris F. Litt, Michael I. Cohen

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Perihepatitis, one manifestation of complicated gonorrhea, is infrequently diagnosed and reported. This study was undertaken to examine the incidence of gonococcal perihepatitis in adolescents as well as to study the effect, if any, of this condition on tests of liver function. Accordingly, the records of 137 adolescents with salpingitis were evaluated. Right upper quadrant tenderness or hepatic enlargement was noted in 27, while amino transferase level elevations were observed in 19 of the 59 in whom these tests were performed. All findings resolved promptly following initiation of intravenous penicillin therapy. The observation of hepatic dysfunction in 27% of these adolescents suggests that perihepatitis occurs more frequently than reported in adults and should be considered in the evaluation of the conditions of adolescents with salpingitis or upper abdominal tenderness.

Original languageEnglish (US)
Pages (from-to)1253-1254
Number of pages2
JournalJAMA: The Journal of the American Medical Association
Issue number12
StatePublished - Sep 15 1978

ASJC Scopus subject areas

  • General Medicine


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