Pathophysiology of childhood OSAS: Structural factors

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The structure and the neural control of the upper airway have evolved to serve four important physiologic functions: (i) respiration, (ii) deglutition, (iii) speech, and (iv) local immunity. The upper airway is collapsible to accommodate these functions. During wakefulness, upper airway collapse can be prevented by an increase in pharyngeal neuromuscular tone (1). However, this mechanism is decreased during sleep, predisposing the upper airway to obstruction (2).

Original languageEnglish (US)
Title of host publicationSleep and Breathing in Children
Subtitle of host publicationDevelopmental Changes in Breathing During Sleep, Second Edition
PublisherCRC Press
Number of pages22
ISBN (Electronic)9781420060836
ISBN (Print)9781420060829
StatePublished - Jan 1 2008

ASJC Scopus subject areas

  • Medicine(all)


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