TY - JOUR
T1 - Outcome of dialysis in children with human immunodeficiency virus infection
AU - Gordillo, Roberto
AU - Kumar, Juhi
AU - Del Rio, Marcela
AU - Flynn, Joseph T.
AU - Woroniecki, Robert P.
PY - 2009
Y1 - 2009
N2 - Human immunodeficiency virus (HIV) infection accounts for an unknown percentage of children with end-stage kidney disease (ESKD). Our objective was to compare the outcome of renal replacement therapy (RRT) in subjects with ESKD due to HIV and other diagnoses and to examine the prevalence of ESKD due to HIV. We analyzed Kt/V, morbidity, mortality, echocardiography, nutritional, and transplant status in 12 dialysis patients with HIV and 32 without HIV followed at our center between February 2002 and February 2007. Body mass index (BMI) was lower and Kt/V higher in HIV than in non-HIV patients. Shortening fraction was significantly lower in HIV patients. There were six deaths in the HIV group and one in the non-HIV group over the study period. Hemodialysis (HD) is the prevalent mode of RRT in HIV in urban settings, and its adequacy as measured by Kt/V was higher in HIV patients than in non-HIV patients. Decreased BMI and cardiovascular disease may be associated with increased mortality in children with HIV on RRT.
AB - Human immunodeficiency virus (HIV) infection accounts for an unknown percentage of children with end-stage kidney disease (ESKD). Our objective was to compare the outcome of renal replacement therapy (RRT) in subjects with ESKD due to HIV and other diagnoses and to examine the prevalence of ESKD due to HIV. We analyzed Kt/V, morbidity, mortality, echocardiography, nutritional, and transplant status in 12 dialysis patients with HIV and 32 without HIV followed at our center between February 2002 and February 2007. Body mass index (BMI) was lower and Kt/V higher in HIV than in non-HIV patients. Shortening fraction was significantly lower in HIV patients. There were six deaths in the HIV group and one in the non-HIV group over the study period. Hemodialysis (HD) is the prevalent mode of RRT in HIV in urban settings, and its adequacy as measured by Kt/V was higher in HIV patients than in non-HIV patients. Decreased BMI and cardiovascular disease may be associated with increased mortality in children with HIV on RRT.
KW - Kt/V
KW - Morbidity
KW - Prevalence and mortality in HIV
KW - Transplantation in HIV
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U2 - 10.1007/s00467-008-0976-x
DO - 10.1007/s00467-008-0976-x
M3 - Article
C2 - 18810503
AN - SCOPUS:59849088949
SN - 0931-041X
VL - 24
SP - 171
EP - 175
JO - Pediatric Nephrology
JF - Pediatric Nephrology
IS - 1
ER -
