TY - JOUR
T1 - Otologic disorders in Turner syndrome
AU - Bois, E.
AU - Nassar, M.
AU - Zenaty, D.
AU - Léger, J.
AU - Van Den Abbeele, T.
AU - Teissier, N.
N1 - Publisher Copyright:
© 2017 Elsevier Masson SAS
PY - 2018/2
Y1 - 2018/2
N2 - Introduction: Patients with Turner syndrome (TS) have craniofacial malformations, such as Eustachian tube hypoplasia and dysfunction and velar dysfunction, which foster acute otitis media. The aim of this study was to inventory pediatric otologic disorders in patients with TS at their first ENT consultation in our center. Patients and methods: We reviewed the ENT consultation data of pediatric TS patients followed in our center between 2005 and 2015: otoscopy, hearing threshold, and history of acute otitis media or ENT surgery. Data were compared according to karyotype: X monosomy (45,X), mosaic (45,X/46,XX), isochromosome (46,Xi [Xq]), X ring chromosome X (XrX), with Y material, and “other”. Results: Ninety patients, with mean age 11.9 years (± 4.8 years) at first ENT consultation, were included: 29% showed tympanic abnormality on otoscopy, 21% had hearing loss, 24% had history of recurrent acute otitis media; 18% had undergone adenoidectomy, 24% T-tube insertion, and 5.6% tympanoplasty. No particular karyotype was associated with higher risk of hearing loss or acute otitis media. Conclusion: Patients with TS showed high prevalence of pediatric otologic disorders; they therefore require close and prolonged ENT follow-up.
AB - Introduction: Patients with Turner syndrome (TS) have craniofacial malformations, such as Eustachian tube hypoplasia and dysfunction and velar dysfunction, which foster acute otitis media. The aim of this study was to inventory pediatric otologic disorders in patients with TS at their first ENT consultation in our center. Patients and methods: We reviewed the ENT consultation data of pediatric TS patients followed in our center between 2005 and 2015: otoscopy, hearing threshold, and history of acute otitis media or ENT surgery. Data were compared according to karyotype: X monosomy (45,X), mosaic (45,X/46,XX), isochromosome (46,Xi [Xq]), X ring chromosome X (XrX), with Y material, and “other”. Results: Ninety patients, with mean age 11.9 years (± 4.8 years) at first ENT consultation, were included: 29% showed tympanic abnormality on otoscopy, 21% had hearing loss, 24% had history of recurrent acute otitis media; 18% had undergone adenoidectomy, 24% T-tube insertion, and 5.6% tympanoplasty. No particular karyotype was associated with higher risk of hearing loss or acute otitis media. Conclusion: Patients with TS showed high prevalence of pediatric otologic disorders; they therefore require close and prolonged ENT follow-up.
KW - Cholesteatoma
KW - Hearing loss
KW - Otitis
KW - Turner syndrome
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U2 - 10.1016/j.anorl.2017.08.006
DO - 10.1016/j.anorl.2017.08.006
M3 - Article
C2 - 28941966
AN - SCOPUS:85029591667
SN - 1879-7296
VL - 135
SP - 21
EP - 24
JO - European Annals of Otorhinolaryngology, Head and Neck Diseases
JF - European Annals of Otorhinolaryngology, Head and Neck Diseases
IS - 1
ER -