Objective cardiac markers and cerebrovascular lesions in Indian seniors

Stephanie H. Charles; Amanda C. Tow; Joe Verghese

doi:10.1016/j.jegh.2014.02.003

Objective cardiac markers and cerebrovascular lesions in Indian seniors

Stephanie H. Charles, Amanda C. Tow, Joe Verghese

Neurology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Cardiovascular risk factors are implicated in cerebrovascular disease, resulting in cognitive impairment. This study investigated the relationship between objective cardiac markers and cerebral changes in older Indian adults with and without dementia. Dementia patients with major electrocardiographic (EKG) abnormalities were 8.19 times more likely to have evidence of stroke on magnetic resonance imaging (MRI) compared with patients with no EKG abnormalities (p<. .05). The relationship between major EKG abnormalities and stroke on MRI was not significant for patients without dementia. Objective cardiac markers may identify MRI cerebrovascular lesions in patients with dementia, and thus guide neuroimaging allocation in resource-poor areas.

Original language	English (US)
Pages (from-to)	245-247
Number of pages	3
Journal	Journal of Epidemiology and Global Health
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/j.jegh.2014.02.003
State	Published - Sep 2014

Keywords

Cerebrovascular disease
Dementia
EKG
Echocardiogram
MRI

ASJC Scopus subject areas

Epidemiology

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10.1016/j.jegh.2014.02.003

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abstract = "Cardiovascular risk factors are implicated in cerebrovascular disease, resulting in cognitive impairment. This study investigated the relationship between objective cardiac markers and cerebral changes in older Indian adults with and without dementia. Dementia patients with major electrocardiographic (EKG) abnormalities were 8.19 times more likely to have evidence of stroke on magnetic resonance imaging (MRI) compared with patients with no EKG abnormalities (p<. .05). The relationship between major EKG abnormalities and stroke on MRI was not significant for patients without dementia. Objective cardiac markers may identify MRI cerebrovascular lesions in patients with dementia, and thus guide neuroimaging allocation in resource-poor areas.",

keywords = "Cerebrovascular disease, Dementia, EKG, Echocardiogram, MRI",

author = "Charles, {Stephanie H.} and Tow, {Amanda C.} and Joe Verghese",

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AU - Tow, Amanda C.

AU - Verghese, Joe

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AB - Cardiovascular risk factors are implicated in cerebrovascular disease, resulting in cognitive impairment. This study investigated the relationship between objective cardiac markers and cerebral changes in older Indian adults with and without dementia. Dementia patients with major electrocardiographic (EKG) abnormalities were 8.19 times more likely to have evidence of stroke on magnetic resonance imaging (MRI) compared with patients with no EKG abnormalities (p<. .05). The relationship between major EKG abnormalities and stroke on MRI was not significant for patients without dementia. Objective cardiac markers may identify MRI cerebrovascular lesions in patients with dementia, and thus guide neuroimaging allocation in resource-poor areas.

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KW - Echocardiogram

KW - MRI

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Objective cardiac markers and cerebrovascular lesions in Indian seniors

Abstract

Keywords

ASJC Scopus subject areas

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