Abstract
Recently, morphometric analysis has shown that the nucleus raphe dorsalis, which is presumed to project diffuse serotonergic fibers to the telencephalon, is affected in Alzheimer's disease. A similar study was conducted in this report in two patients with parkinsonism-dementia complex of Guam and a Guamanian control. It demonstrated a significant reduction in the number of large neurons, and the presence of abundant Alzheimer's neurofibrillary tangles in this nucleus.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 296-299 |
| Number of pages | 4 |
| Journal | Acta Neuropathologica |
| Volume | 67 |
| Issue number | 3-4 |
| DOIs | |
| State | Published - Sep 1 1985 |
Keywords
- Alzheimer's disease
- Morphometry
- Neurofibrillary tangles
- Nucleus raphe dorsalis
- Parkinsonism-dementia complex of Guam
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Clinical Neurology
- Cellular and Molecular Neuroscience