Abstract
Two nuclear receptors of xenobiotic drugs, PXR and CAR, are central regulators of detoxification enzymes. New studies extend the role of these receptors to a natural detoxification process. They coordinate induction of proteins for storage, glucuronidation, and canalicular transport of bilirubin.
Original language | English (US) |
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Pages (from-to) | 607-608 |
Number of pages | 2 |
Journal | Developmental cell |
Volume | 4 |
Issue number | 5 |
DOIs |
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State | Published - May 2003 |
ASJC Scopus subject areas
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- Developmental Biology
- Cell Biology