Normobaric and Hyperbaric Oxygen Therapy for Ischemic Stroke and Other Neurological Conditions

Ari Moskowitz, Yu Feng Yvonne Chan, Aneesh B. Singhal

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationChemistry and Biochemistry of Oxygen Therapeutics
Subtitle of host publicationFrom Transfusion to Artificial Blood
PublisherJohn Wiley and Sons
Number of pages19
ISBN (Print)9780470686683
StatePublished - Jul 4 2011
Externally publishedYes


  • Centers for Disease Control (CDC) estimates - cerebrovascular diseases, cause of death in the United States
  • HBO use in deep-sea divers - decompression sickness ("the bends") and arterial gas embolism
  • Hyperbaric oxygen therapy - and HBO use in organ ischemia
  • Hyperoxia, reducing cyclooxygenase-2 (COX-2) mRNA and MMP-9 - and intercellular adhesion molecule-1 (ICAM-1) levels
  • NBO therapy, accessible - costing less, pleasant for patients, than the HBO
  • Normobaric and hyperbaric oxygen therapy - ischemic stroke, other neurological conditions
  • Normobaric oxygen therapy - 100% oxygen at atmospheric pressure, via face mask
  • Oxygen therapy in acute ischemic stroke (AIS) - hyperoxia in cerebral ischemia
  • Preclinical testing, and therapeutic time window, dosage - in stroke subtypes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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