Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity

Junko Asada-Kamiguchi; Tomotsugu Tabata; Zoran B. Popovic; Neil L. Greenberg; Yong Jin Kim; Mario J. Garcia; Don W. Wallick; Kent A. Mowrey; Shaowei Zhuang; Youhua Zhang; Todor N. Mazgalev; James D. Thomas; Richard A. Grimm

doi:10.1093/ejechocard/jep083

Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity

Junko Asada-Kamiguchi, Tomotsugu Tabata, Zoran B. Popovic, Neil L. Greenberg, Yong Jin Kim, Mario J. Garcia, Don W. Wallick, Kent A. Mowrey, Shaowei Zhuang, Youhua Zhang, Todor N. Mazgalev, James D. Thomas, Richard A. Grimm

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Aims: To elucidate the usefulness of the early diastolic mitral flow propagation velocity (V_p) obtained from colour M-mode Doppler for non-invasively assessing left-ventricular (LV) relaxation during atrial fibrillation (AF). Methods and results: Ten healthy adult dogs were studied to correlate V_p with the invasive minimum value of the first derivative of LV pressure decay (dP/dt_min) and the time constant of isovolumic LV pressure decay (τ) at baseline, during rapid and slow AF, and during AF after inducing myocardial infarction. There were significant positive and negative curvilinear relationships between V_p and dP/dt_min and τ, respectively, during rapid AF. After slowing the ventricular rate, the average value of V_p increased, while dP/dt_min increased and τ decreased. After inducing myocardial infarction, the average value of V_p decreased, while dP/dtmin decreased and τ increased. Conclusion The non-invasively obtained V_p evaluates LV relaxation even during AF regardless of ventricular rhythm or the presence of pathological changes.

Original language	English (US)
Pages (from-to)	826-832
Number of pages	7
Journal	European Journal of Echocardiography
Volume	10
Issue number	7
DOIs	https://doi.org/10.1093/ejechocard/jep083
State	Published - Oct 2009
Externally published	Yes

Keywords

Atrial fibrillation
Mitral flow propagation velocity
The first derivative of left ventricular pressure decay
The time constant of isovolumic left ventricular pressure decay

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1093/ejechocard/jep083

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Asada-Kamiguchi, J., Tabata, T., Popovic, Z. B., Greenberg, N. L., Kim, Y. J., Garcia, M. J., Wallick, D. W., Mowrey, K. A., Zhuang, S., Zhang, Y., Mazgalev, T. N., Thomas, J. D., & Grimm, R. A. (2009). Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity. European Journal of Echocardiography, 10(7), 826-832. https://doi.org/10.1093/ejechocard/jep083

Asada-Kamiguchi, J, Tabata, T, Popovic, ZB, Greenberg, NL, Kim, YJ, Garcia, MJ, Wallick, DW, Mowrey, KA, Zhuang, S, Zhang, Y, Mazgalev, TN, Thomas, JD & Grimm, RA 2009, 'Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity', European Journal of Echocardiography, vol. 10, no. 7, pp. 826-832. https://doi.org/10.1093/ejechocard/jep083

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title = "Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity",

abstract = "Aims: To elucidate the usefulness of the early diastolic mitral flow propagation velocity (Vp) obtained from colour M-mode Doppler for non-invasively assessing left-ventricular (LV) relaxation during atrial fibrillation (AF). Methods and results: Ten healthy adult dogs were studied to correlate Vp with the invasive minimum value of the first derivative of LV pressure decay (dP/dtmin) and the time constant of isovolumic LV pressure decay (τ) at baseline, during rapid and slow AF, and during AF after inducing myocardial infarction. There were significant positive and negative curvilinear relationships between Vp and dP/dtmin and τ, respectively, during rapid AF. After slowing the ventricular rate, the average value of Vp increased, while dP/dtmin increased and τ decreased. After inducing myocardial infarction, the average value of Vp decreased, while dP/dtmin decreased and τ increased. Conclusion The non-invasively obtained Vp evaluates LV relaxation even during AF regardless of ventricular rhythm or the presence of pathological changes.",

keywords = "Atrial fibrillation, Mitral flow propagation velocity, The first derivative of left ventricular pressure decay, The time constant of isovolumic left ventricular pressure decay",

author = "Junko Asada-Kamiguchi and Tomotsugu Tabata and Popovic, {Zoran B.} and Greenberg, {Neil L.} and Kim, {Yong Jin} and Garcia, {Mario J.} and Wallick, {Don W.} and Mowrey, {Kent A.} and Shaowei Zhuang and Youhua Zhang and Mazgalev, {Todor N.} and Thomas, {James D.} and Grimm, {Richard A.}",

year = "2009",

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doi = "10.1093/ejechocard/jep083",

language = "English (US)",

volume = "10",

pages = "826--832",

journal = "European Journal of Echocardiography",

issn = "1525-2167",

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T1 - Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity

AU - Asada-Kamiguchi, Junko

AU - Tabata, Tomotsugu

AU - Popovic, Zoran B.

AU - Greenberg, Neil L.

AU - Kim, Yong Jin

AU - Garcia, Mario J.

AU - Wallick, Don W.

AU - Mowrey, Kent A.

AU - Zhuang, Shaowei

AU - Zhang, Youhua

AU - Mazgalev, Todor N.

AU - Thomas, James D.

AU - Grimm, Richard A.

PY - 2009/10

Y1 - 2009/10

N2 - Aims: To elucidate the usefulness of the early diastolic mitral flow propagation velocity (Vp) obtained from colour M-mode Doppler for non-invasively assessing left-ventricular (LV) relaxation during atrial fibrillation (AF). Methods and results: Ten healthy adult dogs were studied to correlate Vp with the invasive minimum value of the first derivative of LV pressure decay (dP/dtmin) and the time constant of isovolumic LV pressure decay (τ) at baseline, during rapid and slow AF, and during AF after inducing myocardial infarction. There were significant positive and negative curvilinear relationships between Vp and dP/dtmin and τ, respectively, during rapid AF. After slowing the ventricular rate, the average value of Vp increased, while dP/dtmin increased and τ decreased. After inducing myocardial infarction, the average value of Vp decreased, while dP/dtmin decreased and τ increased. Conclusion The non-invasively obtained Vp evaluates LV relaxation even during AF regardless of ventricular rhythm or the presence of pathological changes.

AB - Aims: To elucidate the usefulness of the early diastolic mitral flow propagation velocity (Vp) obtained from colour M-mode Doppler for non-invasively assessing left-ventricular (LV) relaxation during atrial fibrillation (AF). Methods and results: Ten healthy adult dogs were studied to correlate Vp with the invasive minimum value of the first derivative of LV pressure decay (dP/dtmin) and the time constant of isovolumic LV pressure decay (τ) at baseline, during rapid and slow AF, and during AF after inducing myocardial infarction. There were significant positive and negative curvilinear relationships between Vp and dP/dtmin and τ, respectively, during rapid AF. After slowing the ventricular rate, the average value of Vp increased, while dP/dtmin increased and τ decreased. After inducing myocardial infarction, the average value of Vp decreased, while dP/dtmin decreased and τ increased. Conclusion The non-invasively obtained Vp evaluates LV relaxation even during AF regardless of ventricular rhythm or the presence of pathological changes.

KW - Atrial fibrillation

KW - Mitral flow propagation velocity

KW - The first derivative of left ventricular pressure decay

KW - The time constant of isovolumic left ventricular pressure decay

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Non-invasive assessment of left ventricular relaxation during atrial fibrillation using mitral flow propagation velocity

Abstract

Keywords

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