Abstract
A 3 1/2-year-old girl with a diagnosis of common acute lymphoblastic leukemia antigen (CALLA)-positive acute lymphoblastic leukemia was noted to be hypertensive and developed a tonic-clonic seizure. Computed tomography scan of the head revealed a right orbital mass. Orbital fine needle aspiration biopsy demonstrated rosette-like arrangements of cells with fibrillar cytoplasmic processes suggesting neuroblastoma. The tumor cells were antineuron-specific enolase positive. The cytologic findings suggested neuroblastoma, a diagnosis confirmed on subsequent work-up. The difficulty in distinguishing neuroblastoma from acute lymphoblastic leukemia in the pediatric patient is discussed in terms of clinical and cytologic features.
Original language | English (US) |
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Pages (from-to) | 158-161 |
Number of pages | 4 |
Journal | Journal of Clinical Neuro-Ophthalmology |
Volume | 11 |
Issue number | 3 |
State | Published - Sep 1991 |
Keywords
- Acute lymphocytic leukemia
- Fine-needle aspiration biopsy
- Neuroblastoma
- Orbit
ASJC Scopus subject areas
- Ophthalmology
- Clinical Neurology