Mutations on the second chromosome affecting the drosophila Eye

Nicholas E. Baker, Kevin Moses, Donna Nakahara, Michael C. Ellis, Richard W. Carthew, Gerald M. Rubin

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


In the developing eye of Drosophila, cell interactions appear to be responsible for organising undifferentiated cells into unit eyes, or ommatidia. Extensive mutagenesis has been used to search for mutations affecting the development and differentiation of ommatidia. These mutations have been characterized using sections of adults and immunocytochemistry of imaginal discs. Fourteen loci on the second chromosome are described that affect the spacing of the preclusters, the differentiation of ommatidial cells, orientation of the ommatidia, or architecture of the adult retina, that cause retinal degeneration in larval or pupal eye discs, or that cause homeotic transformation of part of the head.

Original languageEnglish (US)
Pages (from-to)85-100
Number of pages16
JournalJournal of Neurogenetics
Issue number2
StatePublished - 1992
Externally publishedYes


  • Cell interactions
  • Drosophila eye
  • Genetic screen
  • Pattern formation

ASJC Scopus subject areas

  • Genetics
  • Cellular and Molecular Neuroscience


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