Multiple endocrine neoplasia type 1: Clinical manifestations and management

Anathea C. Powell, Steven K. Libutti

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Scopus citations


Multiple endocrine neoplasia type I (MEN-1) is an autosomal dominant syndrome associated with anterior pituitary, parathyroid, and enteropancreatic endocrine tumors as well as other endocrine and nonendocrine tumors [1]. MEN-1 is defined as the presence of two of three main MEN-1-related manifestations, or at least one manifestation plus a first degree relative with at least one MEN-1-related manifestation [1,2]. The estimated prevalence of MEN-1 ranges from 1 in 10,000 to 1 in 100,000 [3], with 43 and 94% penetrance of MEN-1 by ages 20 and 50, respectively [4].

Original languageEnglish (US)
Title of host publicationEndocrine Neoplasia
EditorsCord Sturgeon
Number of pages16
StatePublished - Jan 1 2010

Publication series

NameCancer Treatment and Research
ISSN (Print)0927-3042

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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