TY - JOUR
T1 - Multifocal choroiditis and panuveitis presenting with progressive equatorial linear streaks
T2 - Evolution of schlaegel lines documented with multimodal imaging
AU - Somkijrungroj, Thanapong
AU - Pearlman, Joel A.
AU - Gonzales, John A.
PY - 2015/6/6
Y1 - 2015/6/6
N2 - Purpose: To describe the progressive, peripheral linear streaks of the equatorial retina, known as Schlaegel lines, in multifocal choroiditis and panuveitis (MCP). Methods: A case report of a 13-year-old girl with MCP showed progression of retinal linear streaks. Extensive systemic and ophthalmologic investigations were performed. Results: Linear streaks in MCP showed progression before the institution of immunomodulatory treatment. Infrared imaging showed hyperreflectivity of the lesions with surrounding hyporeflectivity. Optical coherence tomography showed elevated and irregular hyperreflectivity of the retinal pigment epithelium and choroidal hyperreflectivity. These findings, including the clinical progression before immunomodulatory therapy and negative systemic evaluation for infectious entities, are consistent with MCP. Conclusion: Patients with linear streaks in the setting of atypical MCP can progress and should be treated with adequate systemic corticosteroids and immunomodulatory agents. This case is unique in that it shows the evolution of Schlaegel lines using a multimodal imaging approach. Multimodal imaging can provide ancillary evidence of disease activity.
AB - Purpose: To describe the progressive, peripheral linear streaks of the equatorial retina, known as Schlaegel lines, in multifocal choroiditis and panuveitis (MCP). Methods: A case report of a 13-year-old girl with MCP showed progression of retinal linear streaks. Extensive systemic and ophthalmologic investigations were performed. Results: Linear streaks in MCP showed progression before the institution of immunomodulatory treatment. Infrared imaging showed hyperreflectivity of the lesions with surrounding hyporeflectivity. Optical coherence tomography showed elevated and irregular hyperreflectivity of the retinal pigment epithelium and choroidal hyperreflectivity. These findings, including the clinical progression before immunomodulatory therapy and negative systemic evaluation for infectious entities, are consistent with MCP. Conclusion: Patients with linear streaks in the setting of atypical MCP can progress and should be treated with adequate systemic corticosteroids and immunomodulatory agents. This case is unique in that it shows the evolution of Schlaegel lines using a multimodal imaging approach. Multimodal imaging can provide ancillary evidence of disease activity.
KW - Schlaegel lines
KW - infrared image
KW - multifocal choroiditis and panuveitis
KW - peripheral linear streaks of the equatorial retina
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U2 - 10.1097/ICB.0000000000000141
DO - 10.1097/ICB.0000000000000141
M3 - Article
C2 - 25790317
AN - SCOPUS:84930465608
SN - 1935-1089
VL - 9
SP - 214
EP - 217
JO - Retinal Cases and Brief Reports
JF - Retinal Cases and Brief Reports
IS - 3
ER -