MRI monitoring of laser ablation using optical flow

Gary P. Zientara, Pairash Saiviroonporn, Paul R. Morrison, Marvin P. Fried, Stephen G. Hushek, Ron Kikinis, Ferenc A. Jolesz

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


The optical flow method is used for visualizing and quantifying the dynamics of tissue changes observed by MRI during thermal ablations. An approach was implemented for parallel two-dimensional optical flow calculations including the replacement of spurious velocities. Velocity magnitude results were found to be accurate in low-noise cases in tests using series of synthetic images. Optical flow results are presented from thermal ablation experiments utilizing a homogeneous polyacrylamide gel phantom and heterogeneous rabbit liver tissue in vivo, exhibiting heating and cooling with the accompanying quantitative characterization of the dilation and contraction of the thermally affected region. Results demonstrate that optical flow is capable of noninvasive real-time monitoring and control of interstitial laser therapy (ILT).

Original languageEnglish (US)
Pages (from-to)1306-1318
Number of pages13
JournalJournal of Magnetic Resonance Imaging
Issue number6
StatePublished - 1998
Externally publishedYes


  • Laser ablation
  • Magnetic resonance imaging
  • Optical flow
  • Therapy monitoring

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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