More than meets the eye: A conserved sensorimotor reflex helps unravel the circuit mechanisms of ASD

Romana J. Hyde, Stephanie Rudolph

Research output: Contribution to journalComment/debatepeer-review

Abstract

Animal models are instrumental to understanding the mechanisms underlying autism spectrum disorder, yet translating human behavioral phenotypes remains challenging. Wang et al. leverage a conserved sensorimotor reflex to elucidate synaptic deficits in Scn2a haploinsufficiency and pilot novel rescue strategies.

Original languageEnglish (US)
Pages (from-to)1375-1378
Number of pages4
JournalNeuron
Volume112
Issue number9
DOIs
StatePublished - May 1 2024

ASJC Scopus subject areas

  • General Neuroscience

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