Secreted and cell-associated plasminogen activator was measured in human skin fibroblasts infected with mycoplasmas. The infected fibroblasts exhibited significantly higher levels of secreted and cell-associated plasminogen activator activity compared to uninfected skin fibroblasts. Subconfluent infected fibroblasts had increased plasminogen activator activity compared to confluent infected fibroblasts. Plasminogen activator may be important in tissue destruction in disease states in which mycoplasma infection has been implicated.
|Number of pages
|Proceedings of the Society for Experimental Biology and Medicine
|Published - Jul 1983
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology