Modern Electron Microscopy Methods for C. elegans

Research output: Chapter in Book/Report/Conference proceedingChapter

77 Scopus citations


From its inception as a model organism 40 years ago, Caenorhabditis elegans was chosen in part for its suitability for study in serial thin sections by electron microscopy. Recent improvements in electron microscopy technology are making this pursuit more reliable and more powerful. In this chapter, we highlight new methods in specimen preparation, imaging, and data analysis. Accurate three-dimensional information can now be obtained for the whole animal at all stages, down to the level of individual organelles and the cytoskeleton.

Original languageEnglish (US)
Title of host publicationMethods in Cell Biology
PublisherAcademic Press Inc.
Number of pages57
StatePublished - 2012

Publication series

NameMethods in Cell Biology
ISSN (Print)0091-679X


  • Fixation
  • Immersion
  • Immunocytochemistry
  • Reconstruction
  • Sectioning
  • Tomography

ASJC Scopus subject areas

  • Cell Biology


Dive into the research topics of 'Modern Electron Microscopy Methods for C. elegans'. Together they form a unique fingerprint.

Cite this