Models for the initiation and growth of extracellular lipid liposomes in arterial intima and valves

Yongyi Yin; Kwang Hee Lim; Sheldon Weinbaum; Shu Chien; David Rumschitzki

Models for the initiation and growth of extracellular lipid liposomes in arterial intima and valves

Yongyi Yin, Kwang Hee Lim, Sheldon Weinbaum, Shu Chien, David Rumschitzki

Pathology

Research output: Contribution to conference › Paper › peer-review

Abstract

A hierarchy of simple nucleation-polymerization models is proposed to describe liposome formation and growth. The cholesterol-fed rabbit intima data seem to result from the short-term nonuniform intimal history of low-density lipoprotein (LDL) supply, which is a consequence of the focal nature of the transarterial-endothelial LDL flow through isolated transient leaky junctions. An appropriate valve water/LDL transport model is combined with the nucleation/polymerization models to explain the data.

Original language	English (US)
Number of pages	1
State	Published - Jan 1 1997
Event	Proceedings of the 1997 Bioengineering Conference - Sunriver, OR, USA Duration: Jun 11 1997 → Jun 15 1997

Other

Other	Proceedings of the 1997 Bioengineering Conference
City	Sunriver, OR, USA
Period	6/11/97 → 6/15/97

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "Models for the initiation and growth of extracellular lipid liposomes in arterial intima and valves",

abstract = "A hierarchy of simple nucleation-polymerization models is proposed to describe liposome formation and growth. The cholesterol-fed rabbit intima data seem to result from the short-term nonuniform intimal history of low-density lipoprotein (LDL) supply, which is a consequence of the focal nature of the transarterial-endothelial LDL flow through isolated transient leaky junctions. An appropriate valve water/LDL transport model is combined with the nucleation/polymerization models to explain the data.",

author = "Yongyi Yin and Lim, {Kwang Hee} and Sheldon Weinbaum and Shu Chien and David Rumschitzki",

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note = "Proceedings of the 1997 Bioengineering Conference ; Conference date: 11-06-1997 Through 15-06-1997",

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T1 - Models for the initiation and growth of extracellular lipid liposomes in arterial intima and valves

AU - Yin, Yongyi

AU - Lim, Kwang Hee

AU - Weinbaum, Sheldon

AU - Chien, Shu

AU - Rumschitzki, David

PY - 1997/1/1

Y1 - 1997/1/1

N2 - A hierarchy of simple nucleation-polymerization models is proposed to describe liposome formation and growth. The cholesterol-fed rabbit intima data seem to result from the short-term nonuniform intimal history of low-density lipoprotein (LDL) supply, which is a consequence of the focal nature of the transarterial-endothelial LDL flow through isolated transient leaky junctions. An appropriate valve water/LDL transport model is combined with the nucleation/polymerization models to explain the data.

AB - A hierarchy of simple nucleation-polymerization models is proposed to describe liposome formation and growth. The cholesterol-fed rabbit intima data seem to result from the short-term nonuniform intimal history of low-density lipoprotein (LDL) supply, which is a consequence of the focal nature of the transarterial-endothelial LDL flow through isolated transient leaky junctions. An appropriate valve water/LDL transport model is combined with the nucleation/polymerization models to explain the data.

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UR - http://www.scopus.com/inward/citedby.url?scp=0030716126&partnerID=8YFLogxK

M3 - Paper

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T2 - Proceedings of the 1997 Bioengineering Conference

Y2 - 11 June 1997 through 15 June 1997

ER -

Models for the initiation and growth of extracellular lipid liposomes in arterial intima and valves

Abstract

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ASJC Scopus subject areas

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