Model of upper airway flow restriction in children with obstructive sleep apnea

D. M. Wootton, A. Guez, P. Vaidyanathan, D. Avinash, J. R. Stablum, J. M. McDonough, J. K. Udupa, R. Arens

Research output: Contribution to journalConference articlepeer-review

2 Scopus citations


Obstructive sleep apnea syndrome (OSAS) in children is correlated to anatomy of the upper airway. Segmented magnetic resonance images of airways from ten OSAS and ten matched control children were used to generate computer flow models. Steady turbulent axisymmetric flow models were solved at peak flow rate to estimate the effect of restricted airway area on pressure drop and resistance. OSAS patients had significantly higher pressure drop and resistance than controls. The magnitude of pressure drop was similar to reported critical airway closure pressures. A subset of OSAS patients had pressure drop and flow resistance similar to controls. Flow modeling may be a useful method to assess the role of anatomy in OSAS.

Original languageEnglish (US)
Pages (from-to)217-218
Number of pages2
JournalProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
StatePublished - 2003
Externally publishedYes
EventProceedings of the IEEE 29th Annual Northeast Bioengineering Conference - Newark, NJ, United States
Duration: Mar 22 2003Mar 23 2003


  • Anatomy
  • CFD
  • Computer Model
  • Fluid Mechanics
  • MRI
  • Obstructive Sleep Apnea

ASJC Scopus subject areas

  • General Chemical Engineering
  • Bioengineering


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