TY - JOUR
T1 - Mitogenic induction of macrophage and neutrophil proliferation in human tonsils
AU - Melamed, Julian
AU - Rubinstein, Arye
PY - 1978/12
Y1 - 1978/12
N2 - A spontaneous and mitogen-induced in vitro release of colony-stimulating activity from human tonsillar cells was observed. This release was absent when T cells were depleted from the cell suspension. Supernates containing colony-stimulating activity induced the proliferation and differentiation of tonsillar precursor cells into monocytes and granulocytes. The maturation and proliferation of monocytes and granulocytes were followed by a continuous flow staining technique, cytochemistry, electro-optical measurement, and signal logic processing employing the automated Hemalog D cell differential counter.
AB - A spontaneous and mitogen-induced in vitro release of colony-stimulating activity from human tonsillar cells was observed. This release was absent when T cells were depleted from the cell suspension. Supernates containing colony-stimulating activity induced the proliferation and differentiation of tonsillar precursor cells into monocytes and granulocytes. The maturation and proliferation of monocytes and granulocytes were followed by a continuous flow staining technique, cytochemistry, electro-optical measurement, and signal logic processing employing the automated Hemalog D cell differential counter.
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U2 - 10.1016/0090-1229(78)90168-X
DO - 10.1016/0090-1229(78)90168-X
M3 - Article
C2 - 310373
AN - SCOPUS:0018165267
SN - 0090-1229
VL - 11
SP - 406
EP - 412
JO - Clinical Immunology and Immunopathology
JF - Clinical Immunology and Immunopathology
IS - 4
ER -