Mitigating contrast-induced acute kidney injury associated with cardiac catheterization

Mark Nunag, Maureen Brogan, Renee Garrick

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Contrast-induced nephropathy, also referred to as contrast-induced acute kidney injury (CIAKI), is among the most common causes of AKI, especially in patients with underlying chronic kidney disease. In addition to the increased cost engendered by the development of CIAKI, several studies have suggested the occurrence of AKI after cardiac procedures is associated with an increase in both morbidity and mortality. This increase in morbidity and mortality occurs after both intravenous and intra-arterial studies. This review focuses on relevant proposed pathophysiological mechanisms, risk factors, and current prophylactic strategies, which may reduce the incidence of CIAKI during cardiac angiographic imaging studies.

Original languageEnglish (US)
Pages (from-to)263-269
Number of pages7
JournalCardiology in review
Issue number6
StatePublished - Nov 2009
Externally publishedYes


  • Bicarbonate therapy
  • Cardiac angiography
  • Contrast-induced AKI
  • Contrast-induced nephropathy
  • N-acetylcysteine

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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