Abstract
The significance of epigenomic aberrations in cancer development has been underscored by the discovery of mutations in key chromatin modifiers, most notably in hematological malignancies. A new study of pediatric acute lymphoblastic leukemia (ALL) demonstrates the usefulness of mapping global epigenetic signatures and applying these data in a framework to identify and characterize underlying somatic genetic alterations in human cancers.
Original language | English (US) |
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Pages (from-to) | 1269-1270 |
Number of pages | 2 |
Journal | Nature Genetics |
Volume | 45 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2013 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics