Microtubule dynamics: Patronin, protector of the minus end

Brian P. O'Rourke, David J. Sharp

Research output: Contribution to journalShort surveypeer-review

5 Scopus citations


It has long been surmised that cellular microtubules are capped at the minus ends to prevent their depolymerization. A recent study provides the first definitive identification of a minus-end-specific capping protein, termed Patronin, which protects the microtubule arrays of both mitotic and interphase cells.

Original languageEnglish (US)
Pages (from-to)R77-R79
JournalCurrent Biology
Issue number2
StatePublished - Jan 25 2011

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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