Metformin associated B12 deficiency

Anand Ajit Kumthekar, Hitesh Vinod Gidwani, Ajit Bhaskar Kumthekar

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


According to the ADA guidelines, metformin and lifestyle modifications are the first line therapies in the treatment of type 2 diabetes mellitus. Metformin does, however, cause vitamin B-12 malabsorption, which may increase the risk of developing vitamin B-12 deficiency - a clinically important and treatable condition. Here we report a case of 60 year old diabetic male presenting with clinical features of Vitamin B-12 deficiency on long term metformin therapy, which was confirmed on investigations. Patient showed symptomatic improvement with change in treatment.

Original languageEnglish (US)
Pages (from-to)58-59
Number of pages2
JournalJournal of Association of Physicians of India
Issue number3
StatePublished - Mar 2012
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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