TY - JOUR
T1 - Metastasis
AU - Lyden, David
AU - Ghajar, Cyrus M.
AU - Correia, Ana Luísa
AU - Aguirre-Ghiso, Julio A.
AU - Cai, Shang
AU - Rescigno, Maria
AU - Zhang, Peiyuan
AU - Hu, Guohong
AU - Fendt, Sarah Maria
AU - Boire, Adrienne
AU - Weichselbaum, Ralph R.
AU - Katipally, Rohan R.
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022/8/8
Y1 - 2022/8/8
N2 - Metastasis, the major cause of cancer death, represents one of the major challenges in oncology. Scientists are still trying to understand the biological basis underlying the dissemination and outgrowth of tumor cells, why these cells can remain dormant for years, how they become resistant to the immune system or cytotoxic effects of systemic therapy, and how they interact with their new microenvironment. We asked experts to discuss some of the unknowns, advances, and areas of opportunity related to cancer metastasis.
AB - Metastasis, the major cause of cancer death, represents one of the major challenges in oncology. Scientists are still trying to understand the biological basis underlying the dissemination and outgrowth of tumor cells, why these cells can remain dormant for years, how they become resistant to the immune system or cytotoxic effects of systemic therapy, and how they interact with their new microenvironment. We asked experts to discuss some of the unknowns, advances, and areas of opportunity related to cancer metastasis.
UR - http://www.scopus.com/inward/record.url?scp=85135731064&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85135731064&partnerID=8YFLogxK
U2 - 10.1016/j.ccell.2022.07.010
DO - 10.1016/j.ccell.2022.07.010
M3 - Comment/debate
C2 - 35944497
AN - SCOPUS:85135731064
SN - 1535-6108
VL - 40
SP - 787
EP - 791
JO - Cancer Cell
JF - Cancer Cell
IS - 8
ER -
