Mercury and Neurodegeneration

Stephanie J.B. Fretham; Ebany J. Martinez-Finley; Michael Aschner

doi:10.1016/B978-0-12-411462-3.00026-6

Mercury and Neurodegeneration

Stephanie J.B. Fretham, Ebany J. Martinez-Finley, Michael Aschner

Molecular Pharmacology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Mercury (Hg) is a naturally occurring, nonessential metal that humans encounter through diet, industry, and natural health products. Hg has wide-reaching effects on the nervous system and is accepted as a neurotoxicant that promotes neurodegeneration and causes neurodevelopmental abnormalities. This chapter discusses sources of Hg exposure, metabolism and dietary interactions, and the biochemical mechanisms through which Hg interferes with neurological function and development.

Original language	English (US)
Title of host publication	Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease
Subtitle of host publication	Prevention and Therapy
Publisher	Elsevier Inc.
Pages	237-244
Number of pages	8
ISBN (Electronic)	9780124115293
ISBN (Print)	9780124114623
DOIs	https://doi.org/10.1016/B978-0-12-411462-3.00026-6
State	Published - 2015

Keywords

Ethylmercury
Mercury
Metabolism
Methylmercury
Neurodevelopment
Oxidative stress
Thiol

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-12-411462-3.00026-6

Cite this

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title = "Mercury and Neurodegeneration",

abstract = "Mercury (Hg) is a naturally occurring, nonessential metal that humans encounter through diet, industry, and natural health products. Hg has wide-reaching effects on the nervous system and is accepted as a neurotoxicant that promotes neurodegeneration and causes neurodevelopmental abnormalities. This chapter discusses sources of Hg exposure, metabolism and dietary interactions, and the biochemical mechanisms through which Hg interferes with neurological function and development.",

keywords = "Ethylmercury, Mercury, Metabolism, Methylmercury, Neurodevelopment, Oxidative stress, Thiol",

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T1 - Mercury and Neurodegeneration

AU - Fretham, Stephanie J.B.

AU - Martinez-Finley, Ebany J.

AU - Aschner, Michael

PY - 2015

Y1 - 2015

N2 - Mercury (Hg) is a naturally occurring, nonessential metal that humans encounter through diet, industry, and natural health products. Hg has wide-reaching effects on the nervous system and is accepted as a neurotoxicant that promotes neurodegeneration and causes neurodevelopmental abnormalities. This chapter discusses sources of Hg exposure, metabolism and dietary interactions, and the biochemical mechanisms through which Hg interferes with neurological function and development.

AB - Mercury (Hg) is a naturally occurring, nonessential metal that humans encounter through diet, industry, and natural health products. Hg has wide-reaching effects on the nervous system and is accepted as a neurotoxicant that promotes neurodegeneration and causes neurodevelopmental abnormalities. This chapter discusses sources of Hg exposure, metabolism and dietary interactions, and the biochemical mechanisms through which Hg interferes with neurological function and development.

KW - Ethylmercury

KW - Mercury

KW - Metabolism

KW - Methylmercury

KW - Neurodevelopment

KW - Oxidative stress

KW - Thiol

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DO - 10.1016/B978-0-12-411462-3.00026-6

M3 - Chapter

AN - SCOPUS:84942604432

SN - 9780124114623

SP - 237

EP - 244

BT - Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease

PB - Elsevier Inc.

ER -

Mercury and Neurodegeneration

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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