Mechanistic role of kinases in the regulation of mitochondrial fitness

Daniela Sorriento, Jessica Gambardella, Antonella Fiordelisi, Bruno Trimarco, Michele Ciccarelli, Guido Iaccarino, Gaetano Santulli

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations


Mounting evidence indicates that mitochondria contain multiple phosphorylation substrates and that protein kinases translocate into mitochondria, suggesting that protein phosphorylation in this organelle could be fundamental for the regulation of its own function. Here we examine the mechanistic role of cellular kinases in the fine regulation of key mitochondrial activities, including mitochondrial quality control, fission/fusion processes, metabolism, and mitophagy.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Number of pages8
StatePublished - May 1 2017
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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