Mapping the homolog of the human Rb1 gene to Chromosome 14 of higher primates

R. S. Verma; K. H. Ramesh; R. V. Samonte; R. A. Conte

doi:10.1007/s003359900175

Mapping the homolog of the human Rb1 gene to Chromosome 14 of higher primates

R. S. Verma, K. H. Ramesh, R. V. Samonte, R. A. Conte

Pathology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The RbI gene has been implicated with retinoblastoma and is located on human Chromosome (Chr) 13q14.2. A unique sequence human RbI cosmid DNA probe has been used to localize this region on apes' Chr 14 by the FISH technique. The conservation of the RbI gene in higher primates at the corresponding equivalent chromosome locus (14q14) of the human may serve as a phylogenetic marker to further trace the evolutionary pathway of human descent.

Original language	English (US)
Pages (from-to)	591-592
Number of pages	2
Journal	Mammalian Genome
Volume	7
Issue number	8
DOIs	https://doi.org/10.1007/s003359900175
State	Published - Jan 1 1996

ASJC Scopus subject areas

Genetics

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abstract = "The RbI gene has been implicated with retinoblastoma and is located on human Chromosome (Chr) 13q14.2. A unique sequence human RbI cosmid DNA probe has been used to localize this region on apes' Chr 14 by the FISH technique. The conservation of the RbI gene in higher primates at the corresponding equivalent chromosome locus (14q14) of the human may serve as a phylogenetic marker to further trace the evolutionary pathway of human descent.",

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AU - Ramesh, K. H.

AU - Samonte, R. V.

AU - Conte, R. A.

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AB - The RbI gene has been implicated with retinoblastoma and is located on human Chromosome (Chr) 13q14.2. A unique sequence human RbI cosmid DNA probe has been used to localize this region on apes' Chr 14 by the FISH technique. The conservation of the RbI gene in higher primates at the corresponding equivalent chromosome locus (14q14) of the human may serve as a phylogenetic marker to further trace the evolutionary pathway of human descent.

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Mapping the homolog of the human Rb1 gene to Chromosome 14 of higher primates

Abstract

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