Abstract
We report a 7-month-old female infant who presented with anuric acute kidney injury and severe hyponatremia (serum sodium 110 mEq/L). The patient was treated with low-dose continuous kidney replacement therapy (CKRT), that is, 85% of total clearance dose divided equally between normonatric (Na 140 mEq/L) replacement and dialysate fluids. The remaining 15% of the clearance was provided by peripheral infusion of dextrose 5% (D5W). The patient's sodium was maintained between 119 mEq/L and 121 mEq/L for the first 24 hours of CKRT. Over the next 2 days, the rate of D5W infusion was slowly decreased while replacement and dialysis flow rates were proportionately increased. Serum sodium was normalised by day 2 of the therapy. The patient had no neurologic sequelae associated with this therapy.
Original language | English (US) |
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Article number | e240308 |
Journal | BMJ case reports |
Volume | 14 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2 2021 |
Keywords
- acute renal failure
- dialysis
- fluid electrolyte and acid-base disturbances
- paediatric intensive care
- paediatrics (drugs and medicines)
ASJC Scopus subject areas
- General Medicine