Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour

Haiying Cheng; David E. Geist; May Piperdi; Renu Virk; Bilal Piperdi

doi:10.1111/j.1440-0960.2008.00495.x

Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour

Haiying Cheng, David E. Geist, May Piperdi, Renu Virk, Bilal Piperdi

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.

Original language	English (US)
Pages (from-to)	41-43
Number of pages	3
Journal	Australasian Journal of Dermatology
Volume	50
Issue number	1
DOIs	https://doi.org/10.1111/j.1440-0960.2008.00495.x
State	Published - Feb 1 2009
Externally published	Yes

Keywords

Methotrexate
Tyrosine kinase inhibitors

ASJC Scopus subject areas

Dermatology

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10.1111/j.1440-0960.2008.00495.x

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abstract = "A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.",

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AU - Piperdi, Bilal

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AB - A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.

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KW - Tyrosine kinase inhibitors

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Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour

Abstract

Keywords

ASJC Scopus subject areas

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